In June several Ukrainian officials admitted that their army had some 700 or even more casualties per day. The numbers were played up to gain access to more 'western' weapons. Since then Ukrainian officials have stated much lower totals of killed and wounded than make sense.
The lowball casualty numbers now are probably convenient to increase moral in Ukraine and to hide from its supporters the inevitable defeat that the Ukrainian army will experience.
This report must be seen in that light.
Russia Hits Train Station in Deadly Attack on Ukraine’s Independence Day – New York Times
A Russian missile hit a train station in eastern Ukraine, killing at least 22 people, President Volodymyr Zelensky said Wednesday, in an attack that came as Ukraine celebrated its Independence Day and brought home the harsh reality of the six-month-old war.
The attack, which took place in an area about 74 miles east of the city of Dnipro in Ukraine-controlled territory, was one of the deadliest strikes on the country’s railways since April, when more than 50 people were killed when a rocket slammed into a crowded railway platform in eastern Ukraine.
The previous attack on a train station which killed some 50 people in Kramatorsk was done with a Ukrainian Tochka-U missile fired from a position under Ukrainian control. Since 2019 the Russian military no longer uses Tochka-U missiles. They have been completely replaced with the more effective Iskander missiles. (A month ago the Donetsk People's Republic was said to have received some old Tochka's for counter battery fire against the Ukrainian units that fire at Donetsk city.)
Now lets look at yesterday's attack which happened near the Chaplino railway station in the Dnepropetrovsk region.
Direct attacks on trains or train stations have been quite unusual in this war. A few months ago there were some night attacks on trains in the western regions of Ukraine hitting at weapon transports that had come in from the 'west'. But an attack with high casualty numbers is unusual. Russia must have been sure that the train transported military and not civilian stuff.
Here are pictures of the result of yesterday's attack:
/Update/
There is also a short video clip which shows that the passenger train was standing next to freight train that carried military vehicles.
/End-update

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That huge attack 'killed at least 22 people'?
Each of the carriages has 10 larger windows each for a compartment that sits six passengers. Additional people may stand or sit in the aisle. At least four carriages were destroyed. If the train has been reasonably full it carried more than 300 passengers. 22 killed is thereby a quite low estimate. In reality there were probably several hundreds casualties.
Here is what the Russian military now says:
An Iskander missile has hit a military train at Chaplino railway station in Dnepropetrovsk Region, destroying over 200 AFU servicemen reserve and 10 units of military equipment on their way to Donbass war zone.
That estimate of casualties of the attack on the Armed Forces of Ukraine sounds more reasonable to me.