The Syrian air-force attacked some Islamic State targets in the eastern Syrian city Raqqa. Many were killed and wounded including civilians.
During the last years the U.S. government would condemn and comment such an attacks as "Assad is killing his own people".
That has changed. The US State Department Bureau of Conflict and Stabilization Operations (CSO) commented on Twitter on the air-raid on Raqqa:

So instead of a demagogic "Assad kills his own people" State CSO now comments "civilians caught in the crossfire".
That quote demonstrates a remarkable change in the State Department's position. Unsurprisingly supporters of the Jihadists and mercenaries fighting the Syrian people were quite enraged about that comment calling it a "new low".
That "new low" change in rhetoric may have come because the air raids by the U.S. air force on Jihadists in Syria also cause civilian death. Or it may be the expression of a genuine change in the position towards the Syrian government. We can not yet tell how far this may go.
How will the State Department now comment when Jabhat al-Nusra, the Islamic State or U.S. supported mercenaries kill civilians during their attacks on the Syrian government? Will those also be "caught in the crossfire"?
When the State Department condemns those civilian death in stronger words than those killed during government action then a genuine, not just rhetoric, change of positions will have occurred.